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Publication AbstractsNaval Aviator with Pituitary Prolactin Secreting Microadenoma: Case Report and Aeromedical ConcernsDavid K. Weiss, M.D., B.A.Aviat Space Environ Med 2000; 71:935-8 AbstractThe potential complications of a large anterior pituitary tumor, including tumor mass effect and the effects of abnormal hormonal regulation, can result in sudden incapacitation and are potentially life threatening. Tumor mass effects include visual disturbances due to compression of the optic chiasm and altered hormonal secretion due to compromised portions of the normal anterior pituitary. Additionally, the tumor may outgrow its own blood supply causing infarction or hemorrhage. Bromocryptine is the primary medication used to treat prolactinomas. Potential side effects of bromocryptine include headaches, orthostatic hypotension, gastrointestinal effects, and psychosis. The effects of long standing untreated hyperprolactinemia are reduced testosterone, frequent headaches, and decreased bone density. This is the case report and discussion concerning a male naval helicopter pilot diagnosed with a relatively small pituitary microadenoma during an evaluation for primary infertility. Detailed discussion of aeromedical concerns, risks, and related cases is presented. This case was reviewed by a Special Board of Flight Surgeons at the Naval Aeromedical and Operational Institute resulting in the first U.S. Navy flight waiver for a patient with a microadenoma to continue on active flight status.Keywords: prolactinoma, microadenoma, bromocryptine, hyperprolactinemia. Information on subscribing, and on obtaining copies of an article or of an entire issue. Table of Contents for Volume 71, Number 9 of the ASME journal.
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